Behavioral and physiological responses to PSP toxins in Mya arenaria populations in relation to previous exposure to red tides
Bibliographic record
Abstract
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout the JournalEditorsTheme Sections MEPS 366:59-74 (2008) - DOI: https://doi.org/10.3354/meps07538 Behavioral and physiological responses to PSP toxins in Mya arenaria populations in relation to previous exposure to red tides Scott P. MacQuarrie1,2,*, V. Monica Bricelj1,3 1National Research Council, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 3Z1, Canada 2Present address: MacQuarrie Research Consultants, 1142 Ketch Harbour Road, Ketch Harbour, Nova Scotia B3V 1K6, Canada 3Present address: Institute of Marine and Coastal Sciences, Rutgers University, New Brunswick, New Jersey 08901, USA *Email: scott@thermalogix.ca ABSTRACT: Paralytic shellfish poisoning (PSP) poses a severe human health risk worldwide and can also adversely affect bivalve populations. This study investigates the intraspecific variation in sensitivity to paralytic shellfish toxins (PSTs) and in toxin accumulation capacity between 2 populations with contrasting histories of PSP in the softshell clam Mya arenaria, a species widely distributed in Atlantic North America. We determine the magnitude and potential ecological consequences of intrinsic variation in toxin susceptibility in M. arenaria, known to have a genetic basis, and the implications for prediction and management of PSTs in regions affected or threatened by PSP expansion. Burrowing, feeding, oxygen consumption (VO2), toxin uptake and survival of 2 test populations were compared during 2 to 3 wk of laboratory exposure to a high-toxicity Alexandrium tamarense strain. Most clams from Lepreau Basin, Bay of Fundy (BF), an area with a long-term history of annual PSP events, exhibited high resistance measured by these parameters, relative to naïve clams from the Lawrencetown Estuary (LE). These were highly sensitive to PSTs, as reflected in significantly reduced clearance and VO2 rates; they also failed to acclimate to the presence of toxins. BF clams attained significantly higher (up to 10-fold) tissue toxicities than LE clams. Toxicity of individual clams from the 2 populations varied up to 40-fold under the same experimental conditions. Toxin-induced mortalities were consistently higher among LE clams (up to 30%) compared to BF clams (2 to 8%). Our findings support the hypothesis that red tides result in natural selection for resistance to PSTs in natural populations. KEY WORDS: Paralytic shellfish toxins · Softshell clams · Mya arenaria · Burrowing · Ecophysiology · Alexandrium tamarense Full text in pdf format PreviousNextCite this article as: MacQuarrie SP, Bricelj VM (2008) Behavioral and physiological responses to PSP toxins in Mya arenaria populations in relation to previous exposure to red tides. Mar Ecol Prog Ser 366:59-74. https://doi.org/10.3354/meps07538 Export citation RSS - Facebook - Tweet - linkedIn Cited by Published in MEPS Vol. 366. Online publication date: August 29, 2008 Print ISSN: 0171-8630; Online ISSN: 1616-1599 Copyright © 2008 Inter-Research.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".