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Inhibitory Effects of Brazilian Propolis on Lipid Accumulation in 3T3-L1 Cells

2014· article· en· W2017099261 on OpenAlexvenueno aff
Yasuhito Nobushi, Yong Kun Park, Ken Yasukawa

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2014
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicBee Products Chemical Analysis
Canadian institutionsnot available
FundersNihon University
KeywordsPropolisIntracellularAntioxidantInhibitory postsynaptic potentialOleanolic acidChemistryBiochemistryTraditional medicineBiologyMedicineFood scienceEndocrinology

Abstract

fetched live from OpenAlex

We here investigated the inhibitory effect of Brazilian propolis on intracellular lipid accumulation. Seven ethanolic extracts of Brazilian propolis were tested for their inhibitory effect on intracellular lipid accumulation in 3T3-L1 cells. Among the seven Brazilian propolis, the extracts AF-08 and AF-18 had inhibitory effects on intracellular lipid accumulation. In particular, the Brazilian propolis AF-08 exhibited a potential inhibitory effect on intracellular lipid accumulation.Thus, these results suggest that the Brazilian propolis AF-08 contributes to the prevention of metabolic syndrome. In addition, five known triterpenoids were isolated from the Brazilian propolis AF-08: betulonic acid, moronic acid, 3-oxo oleanolic acid, masticadienonic acid, and anwnweizonic acid. Four of the triterpenoids exhibited an inhibitory effect on intracellular lipid accumulation. Thus, these triterpenoids may be important as antiobesity agents that inhibit the metabolic syndrome.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.031
Threshold uncertainty score0.112

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.299
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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