The Effect of 3,5,3′-Triiodothyronine on Phosphoenolpyruvate Carboxykinase, Fatty Acid Synthetase and Malic Enzyme Activity of Liver and Brown Fat of Fetal and Neonatal Rats
Bibliographic record
Abstract
Pregnant rats were injected with triiodothyronine (T3) on the 19th and 20th days of pregnancy. This elevated fetal T3 plasma values and caused a large rise in fetal liver phosphoenolpyruvate carboxykinase (PEPcK) activity. At the same time PEPcK activity in fetal brown fat was inhibited. Essentially the same effect of T3 was also noted when injected into postnatal rats. T3 injections also elevated fatty acid synthetase activity in brown fat of weanling rats but, in contrast to corticosteroids, had no effect earlier in life. No effect was noted in the liver, except a slight decrease in the fetus. T3 injections to suckling rats elevated plasma levels of insulin and glucagon within 24 h.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".