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Record W2017859753 · doi:10.1118/1.4814853

SU‐E‐T‐419: To Validate Dose Delivery in Static Field Stereotactic Body Radiation Therapy (SBRT) of Lung Cancer

2013· article· en· W2017859753 on OpenAlexaboutno aff
C Joshi, LM Garcia, T Olding, K M Alexander, T. Owen, A Kerr

Bibliographic record

VenueMedical Physics · 2013
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsnot available
Fundersnot available
KeywordsIonization chamberDosimetryImaging phantomNuclear medicineDose profileMaterials scienceRadiation treatment planningIsocenterLinear particle acceleratorMedical imagingRadiosurgeryRadiation therapyPhysicsBiomedical engineeringOpticsMedicineBeam (structure)RadiologyIon

Abstract

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Purpose: To validate dose delivery in static field stereotactic body radiation therapy (SBRT) of lung cancerMethods: An Exradin A16 0.007cc ion chamber, EBT3 Gafchromic film and Fricke‐Xylenol‐Orange‐Gelatin (FXG) gel dose measurements were performed providing measurements for point, planar and volumetric dose comparisons. CT images (GE Lightspeed RT16 CTSIM) of a Quasar respiratory motion phantom (Modus Medical) with stationary and moving inserts were acquired. Respiratory motion was recorded using a Varian RPM system. Standard cedar inserts with 3cm diameter solid tumors for the ion chamber and film, and an in‐house fabricated custom insert for FXG gel were used. Internal target volumes (ITV) were obtained from 4DCT scans. A typical 15BPM, 20mm amplitude peak‐to‐peak breathing pattern for ion chamber; and sinusoidal 15BPM/10mm respiratory cycles for film and gel dosimetry were used. Nine‐field SBRT plans using 6MV beams were calculated on Eclipse treatment planning system (v10.0; Varian). CBCT scans were used to reproduce the treatment setup; and irradiations were performed on a Trilogy (Varian) linear accelerator. Percentage dose difference and gamma analysis for 3% dose difference and 3mm distance‐to‐agreement were used to compare measured and calculated dose distributions. Results: Measured vs. calculated point dose differences (at a point inside the ITV) for the moving insert geometry were −2.1%, −1.5% and −0.5% for the ion chamber, film and gel measurements, respectively. The planar and volumetric gamma analysis of measured and calculated dose distributions for moving insert geometry showed 99.9% agreements for both EBT3 film and FXG gel dosimetry. Similar comparisons for a stationary insert geometry showed 100% and 98.5% agreements for film and gel measurements, respectively. Conclusion: A consistent level of agreement observed between measured and calculated doses for the point, planar and volumetric dose measurements validates the lung SBRT dose delivery. Research funding support provided by the Canadian Institutes of Health Research (CIHR)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.311
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2013
Admission routes1
Has abstractyes

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