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Record W2018514314 · doi:10.1159/000226541

The Value of a Monoclonal Anti-Epithelial Antibody (mAB lu-5) in the Differential Diagnosis of Tumors

2009· article· en· W2018514314 on OpenAlexaff
Bibi A. Miraliakbari, K Kovács

Bibliographic record

VenueOncology · 2009
Typearticle
Languageen
FieldMedicine
TopicOvarian cancer diagnosis and treatment
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
FundersUniversität Basel
KeywordsMonoclonal antibodyImmunohistochemistryImmunostainingPathologyDifferential diagnosisEpitheliumBiologyAntibodyMonoclonalMedicineImmunology

Abstract

fetched live from OpenAlex

The usefulness of a monoclonal anti-epithelial antibody, mAB lu-5, was assessed in the histologic differential diagnosis of 102 formalin-fixed, paraffin-embedded tumors including various carcinomas, sarcomas and lymphomas. A variety of nontumorous tissues were also evaluated. Although mAB lu-5 failed to provide conclusive results in a few cases, in general, it was found to be a reliable immunohistochemical marker of tumorous and nontumorous epithelial cells. Immunostaining with mAB lu-5 did not distinguish between tumorous and nontumorous tissues and between benign and malignant tumors. Further work is required to clarify the significance of strong immunoreactivity noted in chorionic epithelium and pituitary corticotrophs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.221
Threshold uncertainty score0.257

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.332
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2009
Admission routes1
Has abstractyes

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