Endocrine responses of<i>Fundulus heteroclitus</i>to effluent from a bleached-kraft pulp mill before and after installation of reverse osmosis treatment of a waste stream
Bibliographic record
Abstract
Abstract Implementation of process changes on the nonbleaching side of bleached kraft pulp mill (BKPM) operations has increased in recent years to maximize resource use and to minimize residual environmental effects of discharged effluents. The objective of this study was to determine if reverse osmosis (RO) treatment of evaporator and digester clean condensates reduced or removed the effects of a BKPM effluent on reproductive endocrine function of the estuarine killifish, Fundulus heteroclitus (mummichog). Comparison of data collected before (1997) and after (1998), the years of the process change, showed that the potential of the combined mill effluent to depress plasma testosterone levels after 30 and 57 d of exposure to an environmentally relevant effluent concentration (1%) was reduced after RO treatment of condensates. However, in vitro production of some sex steroids was depressed with a 1% effluent exposure after the process change. In addition, in 1998, depression of plasma testosterone levels in effluent-exposed fish was present at higher effluent concentrations (5%). These results are significant because they suggest that condensates may be a source of endocrine-disrupting compounds in BKPM effluents and RO may reduce their discharge.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".