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Record W2018774180 · doi:10.1159/000241397

Development of Proteolytic Activity in Rabbit Fetal Intestine

2009· article· en· W2018774180 on OpenAlexafffund
Pierre-R. Morin, Michel Potier

Bibliographic record

VenueBiology of the Neonate · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDigestive system and related health
Canadian institutionsUniversité de MontréalCentre Hospitalier Universitaire Sainte-Justine
FundersBayer CanadaMashhad University of Medical SciencesCystic Fibrosis Foundation
KeywordsHemoglobinFetusProteolytic enzymesIncubationSubstrate (aquarium)ChemistryGestationBiochemistryProteolysisHydrolysisChromatographyBiologyAndrologyInternal medicineEndocrinologyEnzymePregnancyMedicine

Abstract

fetched live from OpenAlex

The development of proteolytic activity was determined in rabbit fetal intestine using 125I-hemoglobin as substrate. This assay method allowed increased sensitivity and complete linearity with incubation time and amount of homogenate protein. The effect of pH on substrate hydrolysis showed two main peaks of activity around pH 5 and 8. The apparent Km of proteolytic activity for the 125I-hemoglobin substrate was 0.57 mg/ml at pH 8. Proteolytic activity increases about 10-fold in fetal rabbit intestine between 21 and 31 days of gestation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.134
Threshold uncertainty score0.210

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.269
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2009
Admission routes2
Has abstractyes

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