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Record W2019899378 · doi:10.1117/12.842078

High-resolution imaging of a corneal incision by second- and third-harmonic generation microscopy

2010· article· en· W2019899378 on OpenAlexaff
L. Jay, C. Dion, A. Brocas, Kanwarpal Singh, J. C. Kieffer, Isabelle Brunette, T. Ozaki

Bibliographic record

VenueProceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced Fluorescence Microscopy Techniques
Canadian institutionsInstitut National de la Recherche ScientifiqueUniversité de MontréalHôpital Maisonneuve-Rosemont
Fundersnot available
KeywordsCorneaMicroscopyEx vivoOpticsSecond-harmonic generationMaterials scienceResolution (logic)Image resolutionBiomedical engineeringIn vivoPhysicsMedicineComputer scienceBiologyArtificial intelligence

Abstract

fetched live from OpenAlex

We demonstrate high spatial resolution imaging of a stromal cut in the ex-vivo pig cornea, using second- and third-harmonic generation microscopy. From these images, we see in detail how the cut affects the corneal layers. In the beginning of the cut, the anterior layers, in which the blade is passing through, are disorganized, which could explain the shadows observed on the images. In the stroma, the cut can be imaged by third harmonic microscopy, probably due to the &chi;<sup>3</sup> contrast. Although the current results were obtained from the healthy ex-vivo cornea, it already allows one to understand the effects of the cut on the tissue characteristics (such as scattering).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.251
Threshold uncertainty score0.796

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.238
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes1
Has abstractyes

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Same venueProceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIESame topicAdvanced Fluorescence Microscopy TechniquesFrench-language works237,207