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Record W2021129775 · doi:10.1586/17512433.2.1.9

Transitioning biomarkers into the clinic

2008· article· en· W2021129775 on OpenAlexaboutno aff
Scott A. Waldman

Bibliographic record

VenueExpert Review of Clinical Pharmacology · 2008
Typearticle
Languageen
FieldMedicine
TopicColorectal Cancer Treatments and Studies
Canadian institutionsnot available
Fundersnot available
KeywordsClinical pharmacologyEditorial boardMedicinePharmacologyLibrary science

Abstract

fetched live from OpenAlex

Scott Waldman is currently the Chairman of the Department of Pharmacology and Experimental Therapeutics and the Director of the Division of Clinical Pharmacology. He is the Samuel MV Professor, Department of Medicine and Biochemistry and Molecular Pharmacology. Waldman's research interests focus on molecular pathways underlying early intestinal tumorigenesis and their utility as novel targeted agents for managing patients with colorectal cancer. Waldman obtained his BSc degree in Biology from the University at Albany, his PhD degree in Anatomy from Thomas Jefferson University and his MD degree from Stanford University. He was a postdoctoral fellow at the University of Virginia and Stanford University in the Division of Clinical Pharmacology. He has received numerous honors and awards. He currently has 20 awarded patents and 30 patents pending related to novel diagnostic, therapeutic and immunological targets for gastrointestinal malignancies. He is a member of several editorial boards and scientific peer-review committees. Waldman has over 200 publications in various journals, including Proceedings of the National Academy of Science, Gastroenterology, Journal of Biological Chemistry and Journal of Clinical Investigation. Waldman has served on many councils and chaired NIH study sections. He is currently a member of the Osler Society and the College of Reviewers for the Canada Research Chairs Program. He is a past member of the American Board of Clinical Pharmacology, a past Regent of the American College of Clinical Pharmacology and a past President of the American Society for Clinical Pharmacology and Therapeutics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.009
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.013
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.003
Scholarly communication0.0060.009
Open science0.0010.003
Research integrity0.0030.007
Insufficient payload (model declined to judge)0.0090.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.509
Teacher spread0.405 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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