MétaCan
Menu
Back to cohort
Record W2021329065 · doi:10.4161/cc.24566

eIF4E3, a new actor in mRNA metabolism and tumor suppression

2013· editorial· en· W2021329065 on OpenAlexaff
Laurent Volpon, Michael J. Osborne, Biljana Culjkovic‐Kraljacic, Katherine L. B. Borden

Bibliographic record

VenueCell Cycle · 2013
Typeeditorial
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPI3K/AKT/mTOR signaling in cancer
Canadian institutionsUniversité de MontréalInstitute for Research in Immunology and Cancer
FundersNational Cancer Institute
KeywordsBiologyMessenger RNACell biologyMetabolismCancer researchGeneticsGeneEndocrinology

Abstract

fetched live from OpenAlex

The eukaryotic translation initiation factor eIF4E is a potent oncogene elevated in an estimated 30% of human cancers.1,2 Its elevation in mouse models and tissue culture is linked to tumorigenesis...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.007
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0030.004
Open science0.0020.001
Research integrity0.0070.017
Insufficient payload (model declined to judge)0.0050.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.236
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueCell CycleSame topicPI3K/AKT/mTOR signaling in cancerFrench-language works237,207