Effects of Daily or Weekly Thermal (Footpad) Stress upon Manifestation of Melanoma Tumours
Bibliographic record
Abstract
A total of 48 C57 male and female mice received thermal stimulation to their footpads either daily, weekly, or never. After either two or three weeks of this treatment the mice were injected to discern if the initiation of carcinogenic cell proliferation during a stressful period would influence the rate of development of the tumour. The latency in days for the onset of a discernable node over the injection site was measured. A statistically significant interaction between the temporal pattern of treatments and sex explained about 25% of the variance in the latency of the appearance of tumours. Post hoc analysis showed the source of interaction involved the group that had not received the thermal stress. The results may suggest that either weekly or daily thermal stress may have reduced the females' resistance to tumorigenesis. However, this pattern and type of stress did not influence the first appearance of these skin tumours in the males.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".