Effects of sex steroids on<i>in vitro</i>gamete release in the sea scallop,<i>Placopecten magellanicus</i>
Why this work is in the frame
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Bibliographic record
Abstract
Summary Effects of estradiol, testosterone and progesterone on 5-HT-induced gamete release were studied in vitro in both sexes of the sea scallop. The results showed that estradiol (10−5–10−8 M in females and 10−5–10−7 M in males) and progesterone (10−7–10−8 M in females and 10−5–10−7 M in males) potentiated gamete release in both sexes, whereas testosterone (10−5–10−7 M) had a facilitatory effect only in males. Pharmacological studies suggested that these effects may be achieved through activation of sex steroid receptors because they were abolished by receptor antagonists (tamoxifen, 1.25 μM; flutamine, 2.5 μM; RU486, 1 μM) and by RNA and protein synthesis inhibitors (actinomycin D, 8 μM; cycloheximide, 10 μM). These findings support a growing body of literature which suggests physiological roles of sex steroids in invertebrates. Furthermore, the results also suggest possible applications in the environmental monitoring of endocrine disrupting chemicals and in bivalve aquaculture. Key words: Placopecten magellanicus estradiolprogesteronetestosteroneserotoninmolluscsteroid receptors
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it