Mixed Lymphocyte Reactivity of Patients with Solid Tumors
Bibliographic record
Abstract
The mixed lymphocyte reactivity of 22 solid tumor patients was studied prior to chemotherapy using the one-way (mitomycin-inactivation) assay. In 21/22 one-way studies the response of control subject cells in control plasma against patient cells were superior to the responses of patient cells in patient plasma against control subject cells. When cultured in control subject plasma, seven patients gave a better response than when cultured in autologous plasma. In eleven one-way studies the responses of control subject lymphocytes to patient lymphocytes were depressed on culture in patient plasma when compared to results obtained when cultured in control subject plasma. The authors conclude that (1) solid tumor patients with advanced disease may have impaired mixed lymphocyte reactivity, and (2) in some instances this depressed lymphocyte function may be due to a plasma factor.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".