Ischemic Perinatal Stroke Secondary to Chorioamnionitis: A Histopathological Case Presentation
Bibliographic record
Abstract
Ischemic perinatal stroke is a serious potential complication of delivery. In utero infection may be responsible for an underestimated proportion of perinatal stroke. Limited literature identifies objective evidence of ischemic perinatal stroke as a consequence of uterine infection. The authors report a neonate with ischemic stroke and documented findings of severe chorioamnionitis with umbilical vein thrombosis. A term neonate, after uneventful pregnancy and delivery, presented on the third day of life with seizures. Investigations for metabolic, electrolyte, infectious, and hypercoaguability derangements were normal. Extensive acute infarction in the left middle cerebral artery territory was diagnosed by magnetic resonance imaging (MRI). Placental histopathology confirmed the presence of chorioamnionitis. On follow-up assessments, mild residual neurologic deficits have persisted. Chorioamnionitis has been correlated with ischemic perinatal stroke. In addition to the recognized inflammatory cascade of in utero infection, umbilical vein thrombosis with subsequent ''paradoxical'' embolization may represent one mechanism responsible for this association.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.003 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".