Metabolism of Subcutaneous Adipose Tissue in the Immediate Postnatal Period of Human Newborns
Bibliographic record
Abstract
The activities of citrate cleavage enzyme (CCE; EC 4.1.3.8), malic enzyme (ME; EC 1.1.1.40), phosphoenol pyruvate carboxykinase (PEPK; EC 2.7.1.40), α-glycerophosphate dehydrogenase (GPD EC 1.1.1.8) and glucose-6-phosphate dehydrogenase (G-6-PD; EC 1.1.1.49) was measured in cytosol of subcutaneous adipose (white) tissue in human new borns and adults. ME activity was highest during the first day of life and then decreased. CCE was higher in the newborn adipose tissue than in adults. G-6-PD and GPD activities were higher in the neonate. No changes were noted with PEPK. Our results obtained on activities of enzymes involved in citrate breakdown (CCE) providing acetylCoA and furnishing ‘reduction potential’ for fatiy acid synthesis (ME, G-6-PD) suggest that fatty acid synthesis decreases rapidly after birth. This decrease in enzymes involved in fatty acid synthesis is faster than the decrease in enzymes involved in glycerol production
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".