Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Since it was posited that a cytoplasmic isoform of PrP may be involved in prion diseases, controversies about the isoform's biogenesis and function have emerged in the literature. While the existence of cytoplasmic PrP in vivo and in different cell cultures systems has now been well-established, whether it has specific activity remains unknown. This review outlines recent evidence about the molecular activity of cytoplasmic PrP. Cytoplasmic PrP inhibits a normal cellular stress response by preventing the assembly of protective mRNA stress granules and the synthesis of heat-shock protein 70 following environmental stress. Interference with the stress response correlates with the coalescence of mRNAs in a large cytoplasmic ribonucleoprotein particle. This particle shares similarities with the chromatoid body, a particle that organizes and controls RNA processing in mammalian germ cells as well as in neurons and stem cells from planarians with high regenerative abilities.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it