Intercellular Exchange of Surface Molecules and its Physiological Relevance
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
For many decades, cellular immunologists have relied on the expression of various cell surface molecules to divide cells into different types and subtypes to study their function. However, in recent years, a large and fast-expanding body of work has described the transfer of surface molecules, including MHC class I and II molecules, between cells, both in vitro and in vivo. The function of this process is still largely unknown, but it is likely to have a significant role in the control of the immune system. It is also likely that this process takes place in a regulated rather than stochastic manner, thus providing another way for the immune system to orchestrate its function. In this review we will summarize the key findings so far, examining the mechanisms of transfer, the consequences of this transfer as shown by in vitro experiments, and possible consequences for the wider immune response.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it