Resistance to Tolerance Induction and Age-Dependent Cellular Changes in SJL Mice
Why this work is in the frame
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Bibliographic record
Abstract
SJL mice became resistant to tolerance induction between the 2nd and 6th week of life. The effect on tolerance induction of radioresistant accessory (A) cells does not depend on the age of the donor, i.e. is the same whether the A-cell donor is 3 or 12 weeks old. In the thymectomized recipient, reconstituted with spleen cells of 12-week-old donors, resistance to tolerance is greater than in the corresponding intact animal. Resistance to tolerance is due to a change in the T cells, occurs at a different rate in the T cells of thymus and spleen, and my be due to change in the relative proportion of different T-cell subpopulations.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it