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Prevalence and Penetrance of Germline BRCA1 and BRCA2 Mutations in a Population Series of 649 Women with Ovarian Cancer

2001· article· en· 992 citations· W2025460005 on OpenAlex· 10.1086/318787

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.010
GPT teacher head0.278
Teacher spread
0.268 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The American Journal of Human Genetics
Topic
BRCA gene mutations in cancer
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Women's College HospitalUniversity of TorontoLunenfeld-Tanenbaum Research InstituteToronto Public Health
Funders
National Cancer Institute
Keywords
PenetranceOvarian cancerMedicineCancerGermline mutationOncologyFirst-degree relativesBreast cancerPopulationInternal medicineBRCA2 ProteinGynecologyMutationBiologyGeneticsFamily historyGenePhenotype
Has abstract in OpenAlex
no