Reply: Breast cancer, human papilloma virus and sexual activities
Bibliographic record
Abstract
There are now five studies, including the report of Akil and co-workers in this issue of the Br J Cancer , for which the relationship between age of women and high-risk human papilloma virus (HPV)-positive breast cancer, has been published. Three of these studies report that the age of women with HPV-positive breast cancer is significantly younger than the women with HPV-negative breast cancer. On an average, Greek women with HPV-positive breast cancer were 15 years, Australian women 8 years, and Canadian and Syrian women were 11 years younger than those with HPV-negative breast cancer ( Kroupis et al, 2006 ; Lawson et al, 2006 ; Akil et al, 2007 ). Two studies report no difference in the age of women with HPV-positive or -negative breast cancer ( Hennig et al, 1999 ; Damin et al, 2004 ). Some details of these studies are shown in Table 1 . Table 1 Average age of women with HPV-positive and HPV-negative breast cancer Full size table
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.017 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.002 | 0.004 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.017 | 0.021 |
| Insufficient payload (model declined to judge) | 0.016 | 0.011 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".