Release of Intracellular Constituents from Rabbit Polymorphonuclear Leukocytes Exposed to Soluble and Insoluble Immune Complexes
Bibliographic record
Abstract
Polymorphonuclear leukocytes (PMNL) obtained from peritoneal exudates of unimmunized rabbits consistently released several intracellular constituents into the suspending medium when incubated with equivalence precipitates, which were prepared with rabbit antiserum to bovine serum albumin (BSA). Identical concentrations (AbN) of soluble immune complexes in antigen excess were neither as potent nor as predictable in triggering these phenomena. Precipitates prepared from antisera at 4 weeks after immunization were slightly more potent than those prepared from 6, 8 or 10-week antisera. On the other hand, soluble complexes prepared from 10-week antisera proved more potent than those derived from antisera of earlier bleedings. When PMNL were harvested from rabbits immunized with BSA and then exposed to immune complexes containing autologous antibodies, the ‘immune’ PMNL appeared to be less responsive to these stimuli when compared to PMNL obtained from unimmunized animals.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".