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Record W2027379996 · doi:10.1021/jp2006149

Examination of the Discrepancy between Size Estimates for Ovalbumin from Small-Angle X-ray Scattering and Other Physicochemical Measurements

2011· article· en· W2027379996 on OpenAlexafffund
David J. Scott, Trushar R. Patel, David M. T. Besong, Jörg Stetefeld, Donald J. Winzor

Bibliographic record

VenueThe Journal of Physical Chemistry B · 2011
Typearticle
Languageen
FieldMaterials Science
TopicCrystallization and Solubility Studies
Canadian institutionsUniversity of Manitoba
FundersCanadian Institutes of Health Research
KeywordsSmall-angle X-ray scatteringVirial coefficientChemistryScatteringOvalbuminMonomerSmall-angle scatteringChemical physicsMoleculeCrystallographyThermodynamicsPhysicsOrganic chemistryPolymerOptics

Abstract

fetched live from OpenAlex

Examination of the solution behavior of ovalbumin by small-angle X-ray scattering, dynamic light scattering, and analytical ultracentrifugation methods confirms its existence as a 44-kDa monomer in 20 mM phosphate, pH 7.0, thereby contradicting the discord introduced by published SAXS studies in favor of a dimeric state for this protein at neutral pH. Although the theoretical interpretation of SAXS measurements considers the consequences of thermodynamic nonideality arising from the repulsive interactions between molecules only if they give rise to a positive second virial coefficient, the fact that A(2) is negative for the present system does not account for the earlier findings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.014
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.276
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2011
Admission routes2
Has abstractyes

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