Bibliographic record
Abstract
No AccessJournal of UrologyEditorial1 May 2006Viral Mediated Gene Therapy for Prostate Cancer—Can We Deliver?is companion ofPolyethylene Glycol (Molecular Weight 400 DA) Vehicle Improves Gene Expression of Adenovirus Mediated Gene Therapy D. Robert Siemens D. Robert SiemensD. Robert Siemens More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(06)00362-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Viral Mediated Gene Therapy for Prostate Cancer—Can We Deliver?." The Journal of Urology, 175(5), pp. 1600–1601 References 1 : Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells. Cancer Gene Ther1994; 1: 107. Google Scholar 2 : Inhibition of the growth of pre-established subcutaneous tumor nodules of human prostate cancer cells by single injection of the recombinant adenovirus p53 expression vector. Int J Cancer1997; 71: 377. Google Scholar 3 : Evaluation of gene transfer efficiency by viral vectors to murine bladder epithelium. J Urol2001; 165: 667. Link, Google Scholar 4 : Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase. Cancer Res1998; 58: 5731. Google Scholar 5 : Biomarker distribution after injection in the canine prostate: implications for gene therapy. BJU Int2000; 86: 1076. Google Scholar 6 : The lymphatics of the prostate. Invest Urol1966; 3: 439. Google Scholar 7 : Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture. Laryngoscope1997; 107: 1378. Google Scholar 8 : Improved efficiency of arterial gene transfer by use of poloxamer 407 as a vehicle for adenoviral vectors. Gene Ther1997; 4: 189. Google Scholar 9 : Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats. Neurosurgery1997; 40: 1027. Google Scholar 10 : Viral vector delivery in solid-state vehicles: gene expression in a murine prostate cancer model. J Natl Cancer Inst2000; 92: 403. Google Scholar Department of Urology and Anatomy and Cell Biology, Queen’s University, Kingston, Ontario© 2006 by American Urological AssociationFiguresReferencesRelatedDetailsRelated articlesJournal of Urology9 Nov 2018Polyethylene Glycol (Molecular Weight 400 DA) Vehicle Improves Gene Expression of Adenovirus Mediated Gene Therapy Volume 175Issue 5May 2006Page: 1600-1601 Advertisement Copyright & Permissions© 2006 by American Urological AssociationMetricsAuthor Information D. Robert Siemens More articles by this author Expand All Advertisement PDF downloadLoading ...
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.002 | 0.004 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.101 | 0.045 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".