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Record W2028133748 · doi:10.1139/v05-175

Reaction intermediates in organic chemistry The “big picture”

2005· article· en· W2028133748 on OpenAlexafffundvenueabout
John Andraos

Bibliographic record

VenueCanadian Journal of Chemistry · 2005
Typearticle
Languageen
FieldChemistry
TopicChemical Reaction Mechanisms
Canadian institutionsYork University
FundersNational Research Council CanadaCurtin University of Technology
KeywordsChemistryPhysical organic chemistryReactivity (psychology)Organic reactionOrganic chemistryReactive intermediateIdentification (biology)Organic synthesisReaction intermediateCatalysis

Abstract

fetched live from OpenAlex

An overview of the discovery of reaction intermediates and associated concepts in physical organic chemistry is presented. Particular attention is paid to chronology of ideas, frequency of occurrence of reaction intermediates in the library of organic reactions used in organic synthesis, and the lexicon of scientific terms used in the language of physical organic chemistry. General logic decision trees are presented for the unique or near unique identification of reaction intermediates based on experimental techniques and common patterns of reactivity documented in the literature over the last century. Contributions made by scientists working in laboratories at Canadian universities and at the National Research Council of Canada are noted throughout.Key words: physical organic chemistry, mechanistic chemistry, reaction intermediates.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.081
Threshold uncertainty score0.989

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0120.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.196
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2005
Admission routes4
Has abstractyes

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