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Record W2029206023 · doi:10.1159/000117943

Benzodiazepine Effect on Information Processing in Generalized Anxiety Disorder

2008· article· en· W2029206023 on OpenAlexaff
Y.D. Lapierre, H.J. Butter, L. Kola Oyewumi

Bibliographic record

VenueNeuropsychobiology · 2008
Typearticle
Languageen
FieldNeuroscience
TopicNeural and Behavioral Psychology Studies
Canadian institutionsRoyal Ottawa Mental Health CentreUniversity of Ottawa
Fundersnot available
KeywordsBromazepamSkin conductancePsychologyAnxietyPlaceboArousalDiazepamAudiologyBenzodiazepinePsychophysiologyGeneralized anxiety disorderPerceptionAnesthesiaPsychiatryNeuroscienceMedicineInternal medicine

Abstract

fetched live from OpenAlex

The present investigation assessed 45 anxious neurotic adult patients treated double-blindly in three randomized drug groups; bromazepam, diazepam and placebo. Non-signal, simple and complex signal stimuli were presented to monitor electrodermal activity changes at baseline, 4 h, 1 week and 14 days of treatment. The results indicate that patients with generalized anxiety disorder treated with bromazepam developed decreased skin conductance during the presentation of visual, auditory, and tactile stimuli presentations. Such skin conductance changes were not significant for patients on diazepam and placebo. Future clinical and research implications of these perceptual and psychophysiological results are discussed in conjunction with the usage of a functional-realistic-instrumental paradigm rather than studying anxiety on an attentional-arousal continuum.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.645
Threshold uncertainty score0.647

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.340
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2008
Admission routes1
Has abstractyes

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