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The application of proteomics to blood banking

2008· article· en· W2029996741 on OpenAlexaff
Peter Schubert, Dana V. Devine

Bibliographic record

VenueISBT Science Series · 2008
Typearticle
Languageen
FieldMedicine
TopicBlood groups and transfusion
Canadian institutionsCanadian Blood ServicesUniversity of British Columbia
Fundersnot available
KeywordsColumbia universityLibrary scienceMedicineOriginal researchCitationPolitical scienceFamily medicineSociologyMedia studiesComputer science

Abstract

fetched live from OpenAlex

Continuous improvement in blood bankingThroughout the world, blood services aim to provide a lifesaving service by ensuring an adequate supply of safe, high-quality blood products.In addition to a critical focus on donor recruitment and testing, haemovigilance and overall blood system management, a continuous effort is in place to improve the quality of the products that are prepared.In order to make quantum improvements to blood products, it is necessary to thoroughly understand the components themselves.While production processes are associated with alterations in red cell [1] or platelet products [2,3], the full spectrum of changes is not yet well-understood.New developments in analytical science provide new tools to explore fundamental problems facing transfusion medicine.Proteomics is one such tool that affords a new examination of these questions.Herein, we summarize the current state of the application of proteomics to the challenges in transfusion medicine, both at the donor assessment level and at the level of component preparation and quality.Others have come before us, and the reader is referred to additional descriptions of the recent advances in the application of proteomics in transfusion medicine summarized in these excellent review articles [4 -7].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0010.003
Scholarly communication0.0030.004
Open science0.0010.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.251
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2008
Admission routes1
Has abstractyes

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