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Record W2032125116 · doi:10.1016/j.juro.2012.09.044

Intravesical Oncoviral Therapy for Bladder Cancer

2012· letter· en· W2032125116 on OpenAlexaffabout
Alan So, Paul S. Rennie, William Jia

Bibliographic record

VenueThe Journal of Urology · 2012
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVirus-based gene therapy research
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineOncolytic virusBladder cancerCancerVesicular stomatitis virusOncolytic adenovirusOncologyInternal medicineVirusImmunology

Abstract

fetched live from OpenAlex

No AccessJournal of UrologyEditorial1 Dec 2012Intravesical Oncoviral Therapy for Bladder Cancer Alan So, Paul S. Rennie, and William Jia Alan SoAlan So , Paul S. RenniePaul S. Rennie , and William JiaWilliam Jia View All Author Informationhttps://doi.org/10.1016/j.juro.2012.09.044AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Intravesical Oncoviral Therapy for Bladder Cancer." The Journal of Urology, 188(6), pp. 2039–2040 References 1 : A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer. J Urol2012; 188: 2391. Link, Google Scholar 2 : Direct endoscopic intratumoral injection of Onyx for the preoperative embolization of a recurrent juvenile nasal angiofibroma. Intervent Neuroradiol2011; 17: 477. Google Scholar 3 : Comparison of intravenous versus intraperitoneal administration of oncolytic herpes simplex virus 1 for peritoneal carcinomatosis in mice. Cancer Gene Ther2009; 16: 291. Google Scholar 4 : Preclinical pharmacology and toxicology of intravenous MV-NIS, an oncolytic measles virus administered with or without cyclophosphamide. Clin Pharmacol Therap2007; 82: 700. Google Scholar 5 : Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death. Int J Cancer2010; 127: 830. Google Scholar 6 : Oncolytic vesicular stomatitis viruses are potent agents for intravesical treatment of high-risk bladder cancer. Cancer Res2008; 68: 4506. Google Scholar Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Surgery, University of British Columbia, Vancouver, British Columbia, Canada© 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 188Issue 6December 2012Page: 2039-2040 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alan So More articles by this author Paul S. Rennie More articles by this author William Jia More articles by this author Expand All Advertisement PDF DownloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.026
Threshold uncertainty score0.086

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0260.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.332
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes2
Has abstractyes

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