Severe Hypomagnesemia Associated With Reversible Subacute Ataxia and Cerebellar Hyperintensities on MRI
Why this work is in the frame
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Bibliographic record
Abstract
INTRODUCTION: Hypomagnesemia has been associated with various neurological symptoms including ataxia. Reversible changes in cerebellar function have been described due to hypertensive changes, eclampsia, and immunosuppressive therapy in the context of posterior reversible encephalopathy syndrome. In this report we document isolated, reversible cerebellar findings with the corresponding neuroimaging correlates associated with critically low magnesium levels. CASE REPORT: A 72-year-old male with metastatic colorectal cancer and short gut syndrome presented with subacute ataxia and cerebellar T2 hyperintensities on magnetic resonance imaging. The patient showed rapid clinical and radiologic improvement in his cerebellar findings after receiving only magnesium supplementation. CONCLUSIONS: Our report suggests that low magnesium levels may mimic the vascular endothelial dysregulation that is seen in the context of rapid rises in blood pressure in both posterior reversible encephalopathy syndrome and eclampsia. This rare case suggests a potential role of magnesium in stabilizing the vascular endothelium and, when deficient, in contributing to cerebral edema of the posterior circulation territories.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it