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Record W2032850900 · doi:10.1051/medsci/200622121013

La protéine prion ne se fait pas prier pour faire des agrégats moléculaires

2006· article· fr· W2032850900 on OpenAlexaff
Kevin Goggin, Xavier Roucou

Bibliographic record

Venuemédecine/sciences · 2006
Typearticle
Languagefr
FieldBiochemistry, Genetics and Molecular Biology
TopicPrion Diseases and Protein Misfolding
Canadian institutionsUniversité de Sherbrooke
Fundersnot available
KeywordsGynecologyMedicine

Abstract

fetched live from OpenAlex

1013 M/S n° 12, vol. 22, decembre 2006 controle de la douleur. De plus, les hormones sexuelles ont tres probablement un role a jouer sur les mecanismes excitateurs et inhibiteurs de la douleur. La testosterone aurait un role protecteur, role qui serait d’ailleurs phylogenetiquement conserve, car la testosterone est hypoalgesique non seulement chez les mammiferes, mais egalement chez certains oiseaux [9]. Les hormones sexuelles femelles, pour leur part, auraient un effet modulateur sur les mecanismes inhibiteurs de la douleur. On peut donc croire que certaines pathologies qui s’accompagnent de douleur chronique sont reliees a des deficiences hormonales produisant des deficiences de mecanismes de freinage de la douleur. Nous pouvons donc imaginer que, dans un futur pas tres lointain, un medecin devra non seulement evaluer les mecanismes excitateurs de la douleur chez un patient atteint de douleur chronique mais egalement l’etat hormonal de la personne. Nous ne sommes peut-etre plus tres loin des analgesiques roses ou bleus ! ‡ Is pain sexist? Endogenous pain mechanisms and sex hormones

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.579
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.284
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2006
Admission routes1
Has abstractyes

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