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Record W2035046899 · doi:10.1083/jcb.201401006

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

2014· article· en· W2035046899 on OpenAlexaff
Nikolaus Pfanner, Martin van der Laan, Paolo Amati, Roderick Capaldi, Amy A. Caudy, Agnieszka Chacińska, Manjula Darshi, Markus Deckers, Suzanne Hoppins, T Icho, Stefan Jakobs, Jianguo Ji, Vera Kozjak‐Pavlovic, Chris Meisinger, Paul R. Odgren, Sang Ki Park, Peter Rehling, Andreas S. Reichert, M. Saeed Sheikh, Susan S. Taylor, Nobuo Tsuchida, Alexander M. van der Bliek, Ida J. van der Klei, Jonathan S. Weissman, Benedikt Westermann, Jiping Zha, Walter Neupert, Jodi Nunnari

Bibliographic record

VenueThe Journal of Cell Biology · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMitochondrial Function and Pathology
Canadian institutionsUniversity of Toronto
FundersNational Institute of General Medical Sciences
KeywordsBiologyInner mitochondrial membraneTranslocase of the inner membraneInner membraneNomenclatureMitochondrionMitochondrial carrierTranslocase of the outer membraneCell biologyATP–ADP translocaseMitochondrial membrane transport proteinBacterial outer membraneBiochemistryZoologyTaxonomy (biology)

Abstract

fetched live from OpenAlex

The mitochondrial inner membrane contains a large protein complex that functions in inner membrane organization and formation of membrane contact sites. The complex was variably named the mitochondrial contact site complex, mitochondrial inner membrane organizing system, mitochondrial organizing structure, or Mitofilin/Fcj1 complex. To facilitate future studies, we propose to unify the nomenclature and term the complex "mitochondrial contact site and cristae organizing system" and its subunits Mic10 to Mic60.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.013
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0070.007
Science and technology studies0.0030.005
Scholarly communication0.0040.004
Open science0.0030.003
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0130.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.220
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations256
Published2014
Admission routes1
Has abstractyes

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