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Record W2036045656 · doi:10.1021/om010166o

Highly Reactive Uranium(III) Polypyrrolide Complexes:  Intramolecular C−H Bond Activation, Ligand Isomerization, and Solvent Deoxygenation and Fragmentation

2001· article· en· W2036045656 on OpenAlexaff
Ilia Korobkov, Sandro Gambarotta, Glenn P. A. Yap

Bibliographic record

VenueOrganometallics · 2001
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsChemistryTetrapyrroleMedicinal chemistryDeprotonationLigand (biochemistry)TransmetalationDeoxygenationPyrroleIsomerizationSolventProtonationPhotochemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The reaction of UX 3 (THF) 4 (X = Cl, I) with the tetraanion of {[(−CH 2 −) 5 ] 4 -calix[4]tetrapyrrole} gave different compounds depending on the uranium halide, the alkali-metal cation (Li vs K), the stoichiometric ratio of ligand to uranium, and the solvent used. Reaction of the potassium salt of the ligand with uranium iodide in THF and in the ratio 1:1 afforded the dinuclear, tetravalent species {[{[(−CH 2 −) 5 ] 4 -calix[4]tetrapyrrole}UK(THF) 3 ] 2 (μ 2 -O)}·2THF ( 1 ). The source of the bridging oxygen atom is a THF deoxygenation process. A reaction carried out under identical conditions but with the tetralithium salt of the calix[4]tetrapyrrole afforded instead intractable material unless a stoichiometric ratio of two ligands per uranium was employed. In this event, a new species, the dinuclear tetravalent species [{[(−CH 2 −) 5 ] 4 -calix[4]pyrrole}ULi(THF) 2 ] 2 ·hexane ( 2 ), was isolated. In this complex, the β-C atom of one of the pyrrole rings of the macrocycle was deprotonated and metalated by uranium of a second identical unit, thus assembling the dinuclear structure. The reaction is not accompanied by loss of hydrogen gas, while the excess ligand is acting as a Brønsted base. An identical reaction carried out by using uranium trichloride afforded instead the mononuclear tetravalent species ({[(−CH 2 −) 5 ] 4 -calix[4]tetrapyrrole}ULi(OC 2 H 5 )(THF) 2 ) ( 3 ). In this compound one pyrrole ring was isomerized by shifting the attachment of the chain from the α- to the β-position. The LiOCH 2 CH 3 unit was generated by another pathway of THF fragmentation. Finally, a reaction carried out in dimethoxyethane with the purpose of preventing oxidative attack to the metal center, afforded the mononuclear trivalent complex [{[(−CH 2 −) 5 ] 4 -calix[4]tetrapyrrole}U(DME)][K(DME)] ( 4 ).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.065
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.217
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations64
Published2001
Admission routes1
Has abstractyes

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