Primary Mediastinal Large B-Cell Lymphoma (Thymic Lymphoma) Imaged With F-18 FDG PET-CT
Bibliographic record
Abstract
Primary mediastinal B-cell lymphoma is believed to arise from a small population of thymic medullary B-cells, and is considered a distinct entity from diffuse large B-cell lymphoma, based on its unique clinical, histopathologic, and molecular features. It represents 2% of all non-Hodgkin lymphomas, and has a propensity to affect young women with a median age of 35 years. It usually presents with a bulky tumor in the anterior mediastinum that is rapidly progressive, causing local compressive symptoms. Although distant spread is infrequent at presentation, this subtype of lymphoma tends to spread to unusual extranodal sites such as liver, kidneys, and central nervous system. We present 2 cases of histologically proven primary mediastinal B-cell lymphoma, which demonstrate this pattern of distant spread to organs including the stomach and pancreas. In these cases, F-18 FDG PET-CT proved very useful in the evaluation of distant spread of the disease.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".