Movement of Calcium Ions and Release of Histamine from Rat Mast Cells
Bibliographic record
Abstract
Rat mast cells were stimulated for histamine release in a medium containing radioactive calcium, by band 2 protein (B2) and compound 48/80. It was found that a significant amount of extracellular calcium was taken up by the stimulated cells. When the histamine release process was divided into two stages by activating the cells at 0 degrees C and then washing them prior to suspending them in Tyrode's solution at 37 degrees C, it was found that calcium uptake by the cells took place at the release stage. This suggests that calcium entry into the cells occurs subsequent to the activation stage. Inhibition of histamine release by 2-deoxyglucose (2-DG) and 2,4-dinitrophenol (DNP) also inhibited the calcium influx into the cells. The present studies also suggest that calcium does not diffuse into the cells as a result of degranulation. These findings have been discussed in relation to the mobilization of intracellular calcium.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".