Adenohypophysial Necrosis in Respirator-Maintained Patients
Bibliographic record
Abstract
Fourteen cases of acute adenohypophysial necrosis were found among 76 patients maintained on mechanical respirators, indicating an increased incidence of adenohypophysial necrosis in these patients (18.4%), compared with that of an unselected autopsy material (1.1 %). Histologically, the lesions corresponded to coagulative infarctions and were due to suppression of blood flow to the anterior lobe. In many cases severe and widespread alterations were noted in the brain which might have interfered with pituitary circulation and by resulting in adenohypophysial ischemia could have been responsible for the development of infarction. In some other cases, however, no significant abnormalities were demonstrated in the brain, indicating that cerebral lesions and the associated elevation of intracranial pressure are not the only causative factors leading to circulatory disturbance of the anterior pituitary. No correlation was found between the duration of respirator therapy, the incidence and extent of adenohypophysial necrosis. Thus, it appears that the role of mechanical respirators is that they ‘buy time’ and by prolonging life they allow the advancement of the lesion to histologically recognizable infarction.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".