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Catalytic hydrogenation of functionalized amides under basic and neutral conditions

2014· article· en· 50 citations· W2037796962 on OpenAlex· 10.1039/c4cy01227e

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

The three-model screen

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All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Catalytic hydrogenation chemistry; a synthetic chemistry question.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

This studies a chemical catalyst and hydrogenation reaction, not research practice.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Domain chemistry paper on amide hydrogenation catalysis; object is chemical reactivity, not research practice.

Abstract

A new, base-free high turnover number (TON) catalyst for hydrogenation of simple and functionalized amides is prepared by reacting [Ru(η<sup>3</sup>-C<sub>3</sub>H<sub>5</sub>)(Ph<sub>2</sub>P(CH<sub>2</sub>)<sub>2</sub>NH<sub>2</sub>)<sub>2</sub>]BF<sub>4</sub> and BH<sub>4</sub><sup>−</sup> under hydrogen.

Stored with the screening record, where it is evidence for the labels above.

The record

Venue
Catalysis Science & Technology
Topic
Asymmetric Hydrogenation and Catalysis
Field
Chemistry
Canadian institutions
Alberta Hospital EdmontonUniversity of Alberta
Funders
Natural Sciences and Engineering Research Council of CanadaUniversity of Alberta
Keywords
CatalysisChemistryCombinatorial chemistryOrganic chemistry
Has abstract in OpenAlex
yes