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Record W2037870552 · doi:10.1016/s1873-9946(09)60283-x

P256 - Epidemiology of inflammatory bowel diseases in northwestern Greece for the years 1981 2007

2009· article· en· W2037870552 on OpenAlexaboutno aff
C. Zois, K. Katsanos, Dimitrios Christodoulou, Gerasimos Baltayiannis, N. Tzambouras, Athanasios Papathanasopoulos, Vasileios Theopistos, Kostas Masalas, Antonis Kogevinas, Moschos A. Papadopoulos, Sophia Georgiou, A. Vlachopoulos, A. Germanopoulos, Dimitris Kourtesas, S. Katsaros, N. Monastiriotis, Nikolaos Kostas, Kostas G. Kistis, Spyridon Filis, T. Pasas, E.V. Tsianos

Bibliographic record

VenueJournal of Crohn s and Colitis · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDepression (economics)Internal medicineAnxietyMarital statusEpidemiologyInflammatory bowel diseaseInfliximabDiseaseLogistic regressionCrohn's diseaseGastroenterologyPsychiatryPopulation

Abstract

fetched live from OpenAlex

factors that could have influence on development of these symptoms. Methods: We performed a study in which we only included CD patients older than 18 years with at least 6 months in remission. CD remission was defined by a Crohn’s disease Activity Index (CDAI) <150 points together with a C-reactive protein <5mg/l. A demographic questionnaire that included age, gender, level of studies, marital status and smoking habits was performed. All patients were clinical stratified by years of disease, location and behaviour of the disease according to the Montreal Classification, perianal disease, extraintestinal manifestations, previous bowel resection and if had previously developed steroid-dependency or steroidresistance. The different treatments which patients maintained remission was also evaluated. Hospital Anxiety and Depression scale (HAD) was performed in all patients. Results are shown in percentages and analyzed by logistic regression, results of p < 0.05 were considered as statically significant. Results: 92 consecutive patients were included; (48 male and 44 female), mean age 37 years, range from 18 to 71). 1 (1%) patient failed to respond correctly to the questionnaire. 36 (39%) of patients presented anxiety symptoms and 22 (24%) presented depression symptoms. Patients who maintained remission with infliximab (IFX) presented more anxiety symptoms than those who received non-biologic therapies (p = 0.04), probably for having to go to the Hospital every 8 weeks despite being well. Patients with previous bowel resections (p < 0.01) and ileal location (p = 0.02) presented more depressive symptoms. Patients who maintained remission with IFX had a lower risk of presenting depressive symptoms (p = 0.02) than those received non-biologic therapies, probably because those patients previously stayed worse and had experimented a more spectacular improvement. Conclusions: Despite staying in clinical remission, an important number of CD patients present anxiety or depressive symptoms. Patients with a previous bowel resection tend to have more depressive symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.262
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

Explore more

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