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Amelanotic Melanoma of the Root of the Tongue in A Canine Patient Treated by Electrochemotherapy

2014· article· en· W2039011107 on OpenAlex
Felipe Maglietti, Sebastián Michinski, I. Ricotti, Pablo Maure, Lluis M. Mir, Nahuel Olaiz, Guillermo Marshall

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Analytical Oncology · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMicrobial Inactivation Methods
Canadian institutionsnot available
FundersSecretaría de Ciencia y Técnica, Universidad de Buenos AiresCentre National de la Recherche ScientifiqueUniversidad de Buenos AiresConsejo Nacional de Investigaciones Científicas y Técnicas
KeywordsElectrochemotherapyMedicineBleomycinTongueSurgeryAdverse effectTongue diseaseMelanomaDiseaseInternal medicinePathologyChemotherapy

Abstract

fetched live from OpenAlex

Background: Electrochemotherapy is a novel tumor treatment routinely used for cutaneous and subcutaneous tumors in human patients in the European Union since 2006. Here we used it to treat an amelanotic melanoma of the root of the tongue in a canine patient. Case Presentation: The patient was a 9 year-old, female, Golden Retriever, dehydrated, cachectic and in a bad general condition due to the difficulty in eating and drinking provoked by the tumor. The procedure was performed with general anesthesia, with intravenous administration of bleomycin, and went uneventful. The only adverse effect was an important swelling of the tongue which lasted 2 days and was controlled with non-steroidal anti-inflammatory drugs. Results and Conclusion: A good local control of the disease was achieved with a 83% reduction of the tumor mass, at day 21 after a single treatment. On the 33rd day the patient died after a digestive hemorrhage not related to the treatment. Electrochemotherapy was found a good approach to locally control the disease. The swelling of the tongue was an important side effect which has to be taken into account when treating this organ, and should be controlled with medication.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.191

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.278
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it