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Record W2039738742 · doi:10.3109/10408444.2011.554793

A review of epidemiologic studies of triazine herbicides and cancer

2011· review· en· W2039738742 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCritical Reviews in Toxicology · 2011
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRetinoids in leukemia and cellular processes
Canadian institutionsPublic Health OntarioUniversity of Toronto
Fundersnot available
KeywordsCancerMedicineLeukemiaLymphomaEpidemiologyOncologyPathologyInternal medicineSarcomaProstateCancer research

Abstract

fetched live from OpenAlex

This is an update of a previous review of epidemiological evidence pertaining to the human carcinogenic potential of triazine herbicides. In 36 studies evaluated, atrazine was the most common triazine investigated. In general the studies were limited by lack of in-depth exposure measurements and by small numbers of subjects with potential high exposure and/or with many years of follow-up since first exposure. Non-Hodgkin lymphoma, prostate cancer, and breast cancer were most frequently investigated. Only one to three analytical or ecological studies investigated Hodgkin lymphoma, leukemia, multiple myeloma, soft tissue sarcoma, hairy-cell leukemia, melanoma, and cancers of the ovary, testes, colon, stomach, lung, brain, bladder, buccal cavity, and pharynx. Results of these studies were typically imprecise and did not form an adequate basis for determining if triazine exposure causes any form of cancer. Collectively, the available epidemiology studies do not provide consistent, scientifically convincing evidence of a causal relationship between exposure to atrazine or triazine herbicides and cancer in humans. Based upon the assessment studies, there is no scientific basis for inferring the existence of a causal relationship between triazine exposure and the occurrence of cancer in humans.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.023
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.806
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.023
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0050.001
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.208
GPT teacher head0.489
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it