P11.01: Amniotic fluid sludge observed during ultrasound examination and prediction of preterm delivery
Bibliographic record
Abstract
To predict when delivery will occur, within 14 days and before 34 weeks' gestation in women with amniotic fluid sludge observed during ultrasound examination. This study includes women at high risk for preterm delivery (history of preterm delivery, preterm pregnancy loss, threatened preterm labor) who underwent a sonographic measurement of cervical length after 18 weeks' gestation. Multiple gestation and patients with cerclage were excluded. Ultrasound images collected were reviewed retrospectively by two independant examinators and were classified into three groups: 1) no amniotic sludge, 2) lightly sludge, 3) amniotic fluid sludge. The outcome measures were delivery within 14 days of examination, delivery before 35 weeks and chorioamnionitis on placental pathology. Chi-Sqared, Kruskal-Wallis and logistic regression analysis were performed. Eighty-nine patients met inclusion criteria. The mean gestation at presentation was 25.8 ± 4.4 weeks and the mean cervical length was 33 ± 12 mm. The prevalence of lightly sludge and amniotic fluid sludge were 9.0% and 5.6% respectively. Delivery within 14 days of examination occurred in 5 (6.6%) cases with no sludge, in 1 (12.5%) case with lightly sludge and in 3 (60.0%) cases with amniotic fluid sludge (p = 0.001). Delivery before 34 weeks occurred in 5 (6.6%), 3 (37.5%), 4 (80.0%), respectively (p < 0.001). Logistic regression analyses demonstrated that presence of amniotic fluid sludge (OR, 13.8; 95% CI, 1.52–125.2) and cervical length less than 25 mm (OR, 6.9; 95% CI, 1.35–35.3) were significant independent predictor of delivery within 14 days and were also independent predictors of delivery prior to 34 weeks ((OR, 45.6; 95% CI, 3.5–592.6) and (OR, 7.3; 95% CI, 1.5–35.0), respectively). In women at high risk for preterm delivery, amniotic fluid sludge appears as a strong and independent factor for subsequent delivery within 14 days.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.017 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".