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Record W2040487446 · doi:10.1109/cibcb.2010.5510482

Functional data classification for temporal gene expression data with kernel-induced random forests

2010· article· en· W2040487446 on OpenAlexafffund
Guangzhe Fan, Jiguo Cao, Jiheng Wang

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsActuaSimon Fraser UniversityUniversity of Waterloo
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsRandom forestKernel (algebra)Computer scienceCurse of dimensionalityArtificial intelligenceKernel methodPattern recognition (psychology)Kernel density estimationVariable kernel density estimationMultivariate statisticsData miningExpression (computer science)Functional data analysisSupport vector machineMachine learningMathematicsStatistics

Abstract

fetched live from OpenAlex

Scientists and others today often collect samples of curves and other functional data. The multivariate data classification methods cannot be directly used for functional data classification because the curse of dimensionality and difficulty in taking in account the correlation and order of functional data. We extend the kernel-induced random forest method for discriminating functional data by defining kernel functions of two curves. This method is demonstrated by classifying the temporal gene expression data. The simulation study and applications show that the kernel-induced random forest method increases the classification accuracy from the available methods. The kernel-induced random forest method is easy to implement by naive users. It is also appealing in its flexibility to allow users to choose different curve estimation methods and appropriate kernel functions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.006
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.012
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.316
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2010
Admission routes2
Has abstractyes

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