Record W2040964350 · doi:10.1038/ng.2608

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

2013· review· en· W2040964350 on OpenAlexaff

Keri L. Monda, Gary K. Chen, Kira C. Taylor, Cameron D. Palmer, Todd L. Edwards, Leslie A. Lange, Maggie C. Y. Ng, Adebowale Adeyemo, Matthew Allison, Lawrence F. Bielak, Guanjie Chen, Mariaelisa Graff, Marguerite R. Irvin, Suhn K. Rhie, Li Guo, Ching‐Ti Liu, Youfang Liu, Yingchang Lu, Michael A. Nalls, Yan V. Sun, Mary K. Wojczynski, Lisa R. Yanek, Melinda C. Aldrich, Adeyinka Ademola, Christopher I. Amos, Elisa V. Bandera, Cathryn H. Bock, Angela Britton, Ulrich Broeckel, Quiyin Cai, Neil E. Caporaso, Chris Carlson, John Carpten, Graham Casey, Wei‐Min Chen, Fang Chen, Yii-Der I. Chen, Charleston W. K. Chiang, Gerhard A. Coetzee, Ellen W. Demerath, Sandra Deming-Halverson, Ryan W Driver, Patricia M. Dubbert, Mary F. Feitosa, Ye Feng, Barry I. Freedman, Elizabeth M. Gillanders, Omri Gottesman, Xiuqing Guo, Talin Haritunians, Tamara Harris, Curtis C. Harris, Anselm Hennis, Dena Hernández, Lorna H. McNeill, Timothy D. Howard, Barbara V. Howard, Virginia J. Howard, Karen Johnson, Sun Jung Kang, Brendan J. Keating, Suzanne Kolb, Lewis H. Kuller, Abdullah Kutlar, Carl D. Langefeld, Guillaume Lettre, Kurt Lohman, Vaneet Lotay, Helen N. Lyon, JoAnn E. Manson, William Maixner, Yan Meng, Kristine R. Monroe, Imran Morhason‐Bello, Adam B. Murphy, Josyf C. Mychaleckyj, Rajiv Nadukuru, Katherine L. Nathanson, Uma Nayak, Amidou N’Diaye, Barbara Nemesure, Suh-Yuh Wu, M. Cristina Leske, Christine Neslund‐Dudas, Marian L. Neuhouser, Sarah J. Nyante, Heather M. Ochs‐Balcom, Adesola Ogunniyi, Temidayo O. Ogundiran, Oladosu Ojengbede, Olufunmilayo I. Olopade, Julie R. Palmer, Edward Ruiz-Narváez, Michael F. Press, Evandine Rampersaud, Laura J. Rasmussen‐Torvik, Jorge L. Rodriguez‐Gil, Babatunde Salako, Eric E. Schadt, Ann G. Schwartz, Daniel Shriner, David S. Siscovick, Shad B. Smith, Sylvia Wassertheil‐Smoller, Elizabeth K. Speliotes, Margaret R. Spitz, Lara Sucheston, Herman A. Taylor, Bamidele O. Tayo, Margaret A. Tucker, David J. Van Den Berg, Digna R. Velez Edwards, John K. Wiencke, Thomas W. Winkler, John S. Witte, Margaret Wrensch, Xifeng Wu, James J. Yang, Albert M. Levin, Taylor Young, Neil A. Zakai, Mary Cushman, Krista A. Zanetti, Jing Hua Zhao, Wei Zhao, Yonglan Zheng, Jie Zhou, Regina G. Ziegler, Joseph M. Zmuda, Jyotika K. Fernandes, Gary S. Gilkeson, Diane L. Kamen, Kelly J. Hunt, Ida J. Spruill, Christine B. Ambrosone, Stefan Ambs, Donna K. Arnett, Larry D. Atwood, Diane M. Becker, Sonja I. Berndt, Leslie Bernstein, William J. Blot, Ingrid B. Borecki, Erwin P. Böttinger, Donald W. Bowden, Gregory L. Burke, Stephen J. Chanock, Jingzhong Ding, David Duggan, Michele K. Evans, Caroline S. Fox, W. Timothy Garvey, Jonathan P. Bradfield, Håkon Håkonarson, Struan F.A. Grant, Ann W. Hsing, Lisa W. Chu, Jennifer J. Hu, Dezheng Huo, Sue A. Ingles, Esther M. John, Joanne M. Jordan, Edmond K. Kabagambe, Sharon L. R. Kardia, Rick A. Kittles, Phyllis J. Goodman, Eric A. Klein, Laurence N. Kolonel, Loı̈c Le Marchand, Simin Liu, Barbara McKnight, Robert C. Millikan, Thomas H. Mosley, Badri Padhukasahasram, L. Keoki Williams, Sanjay R. Patel, Ulrike Peters, Curtis A. Pettaway, Patricia A. Peyser, Bruce M. Psaty, Susan Redline, Charles N. Rotimi, Benjamin A. Rybicki, Michèle M. Sale, Pamela J. Schreiner, Lisa B. Signorello, Andrew B. Singleton, Janet L. Stanford, Sara S. Strom, Michael J. Thun, Mara Z. Vitolins, Wei Zheng, Jason H. Moore, Scott M. Williams, Shamika Ketkar, Xiaofeng Zhu, Alan B. Zonderman, Charles Kooperberg, George Papanicolaou, Brian E. Henderson, Alex P. Reiner, Joel N. Hirschhorn, Ruth J. F. Loos, Kari E. North, Christopher A. Haiman

Bibliographic record

VenueNature Genetics · 2013

Typereview

Languageen

FieldBiochemistry, Genetics and Molecular Biology

TopicGenetic Associations and Epidemiology

Canadian institutionsUniversité de MontréalMontreal Heart Institute

FundersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute on Minority Health and Health DisparitiesNational Center for Research ResourcesU.S. National Library of MedicineNational Institute of Environmental Health SciencesNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational Institute of Allergy and Infectious DiseasesNational Institute of Neurological Disorders and StrokeNational Institute of General Medical SciencesNational Center for Advancing Translational SciencesNational Human Genome Research InstituteNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteU.S. Public Health ServiceNational Institute on AgingNational Cancer InstituteNational Institutes of Health

KeywordsGenome-wide association studyBiologyGenetic genealogyBody mass indexGeneticsLocus (genetics)Ancestry-informative markerGenotypingSingle-nucleotide polymorphismGenetic associationMeta-analysisDemographyGenotypePopulationMedicineInternal medicineGene

DOI10.1038/ng.2608

Abstract

fetched live from OpenAlex

No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001

metaresearch head score (Gemma)0.000

Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated

Candidate categoriesMeta-epidemiology (narrow), Research integrity

Consensus categoriesnone

DomainCandidate signal: none · Consensus signal: none

Study designCandidate signal: Meta-analysis · Consensus signal: none

GenreCandidate signal: Review · Consensus signal: Review

Teacher disagreement score0.582

Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

Category	Codex	Gemma
Metaresearch	0.001	0.000
Meta-epidemiology (narrow)	0.001	0.000
Meta-epidemiology (broad)	0.004	0.002
Bibliometrics	0.000	0.001
Science and technology studies	0.000	0.000
Scholarly communication	0.000	0.000
Open science	0.001	0.000
Research integrity	0.003	0.001
Insufficient payload (model declined to judge)	0.000	0.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065

GPT teacher head0.344

Teacher spread0.279 · how far apart the two teachers sit on this one work

Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it