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Record W2041151247 · doi:10.4161/worm.19560

Introducing Worm

2012· article· en· W2041151247 on OpenAlexaff
Harald Hutter

Bibliographic record

VenueWorm · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Aging, and Longevity in Model Organisms
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsZoologyBiology

Abstract

fetched live from OpenAlex

In 1963 Sydney Brenner proposed to study the development of multi-cellular organisms using a genetic approach in a simple animal. He settled on a small, transparent nematode, Caenorhabditis elegans, which develops quickly and is anatomically simple with less than a thousand somatic cells. Almost half a century later there are many more researchers studying C. elegans than there are somatic cells in this animal and the areas of research have expanded to cover many aspects of cell and developmental biology, behavior, physiology and more recently evolutionary and population biology. Pioneering studies have led to Nobel prizes for six C. elegans researchers in the last decade, illustrating the importance of the discoveries made by studying this relatively simple metazoan. C. elegans researchers have always maintained a strong sense of community and this collegiality is also visible in the collection and dissemination of research results. Wormbase, the main database integrating molecular, genetic and phenotypic data on genes and genomes, has a long history of collecting and presenting data contributed by researchers independently of official publications. This information-sharing spirit is also apparent in the “Worm Breeder’s Gazette”, which provides an informal way to report a variety of interesting results without official peer-review process. Despite this collective intelligence, the current size of the worm field makes it difficult to keep up with all the information. More and more interesting findings never make it into official publications, in part because it can be frustrating to see a manuscript through the publication process. This new journal can help to reverse this trend, insuring that information gets out to the community in a timely manner. Worm aims to provide a straightforward and quick publication process. Editors and reviewers are active researchers of the same model organism with an intimate knowledge of its advantages and limitations at the experimental level. Time and again, discoveries from nematode researchers have implications for other researchers working on a seemingly unrelated question. Worm invites submissions from all areas of research using C. elegans and other nematodes. Sometimes results are intriguing, but do not provide immediate “mechanistic insights”. Nevertheless they might be of immediate interest to the research community. Worm offers the opportunity to submit such results as short communications. More and more studies now cross the borders of traditional disciplines, so that they might not be suitable for topic-oriented journals. Worm offers an opportunity to present exciting results irrespective of the topic of research. Worm also publishes techniques or methods papers of relevance to nematode researchers. While C. elegans currently is the most prominent nematode, it is certainly not the only one studied. With more and more genome sequence information available, research on other nematodes is likely to expand even further. We encourage all nematode researchers to consider Worm as a journal for the dissemination of their discoveries. We are optimistic that this journal will provide a place for nematode researchers to submit some of their most interesting findings. I hope you will enjoy the first issue and keep this journal in mind not just as reader, but also as author.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.354
Threshold uncertainty score0.479

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.230
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2012
Admission routes1
Has abstractyes

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