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Record W2041341702 · doi:10.1139/z02-121

Is prolactin responsible for avian, saurian, and mammalian relapse and periodicity of fever in malarial infections?

2002· article· en· W2041341702 on OpenAlexvenueaboutno aff
Roy Douglas Pearson

Bibliographic record

VenueCanadian Journal of Zoology · 2002
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicReproductive Physiology in Livestock
Canadian institutionsnot available
Fundersnot available
KeywordsBiologyMalariaProlactinProinflammatory cytokineAvian malariaReproductionImmunologyPhysiologyHormoneZoologyEndocrinologyPlasmodium falciparumEcologyGametocyteInflammation

Abstract

fetched live from OpenAlex

P.C.C. Garnham came to Toronto nearly 35 years ago to see if he, and the laboratory of A.M. Fallis, could unravel the enigma of "relapsing" malaria-like infections in migrating ducks (to Algonquin Park, Ontario). At the time, not enough was known about the endocrinology of avian migration and reproduction. Now a growing body of indirect evidence seems to point to a role for prolactin in many of the uniquely pathologic phenomena witnessed in malarial infections. Arguments in favour of the involvement of prolactin, as both a developmental hormone and a proinflammatory cytokine, in the pathology of relapse, fever, anaemia, and maternal malaria are presented in the hope that experiments to test such involvement will be designed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.229
Teacher spread0.199 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2002
Admission routes2
Has abstractyes

Explore more

Same venueCanadian Journal of ZoologySame topicReproductive Physiology in LivestockFrench-language works237,207