MétaCan
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Warfarin: almost 60 years old and still causing problems

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

About CanadaIts subject is Canada, wherever its authors sit.

No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Scholarly communicationNon-randomized trialObservationalCase reportSimulation or modellingNot applicable
Classifier consensus
N/A
Teacher imitation scores

Codex

Other design0.213
Simulation or modelling0.072
Not applicable0.041
Observational0.015
Scholarly communication0.014
Research integrity0.008
Case report0.007
Theoretical or conceptual0.006
Science and technology studies0.002
Bench or experimental0.002
Metaresearch0.002
Systematic review0.001
Non-randomized trial0.000
Open science0.000
Randomized trial0.000
Meta-analysis0.000
Meta-epidemiology (broad)0.000
Qualitative0.000
Meta-epidemiology (narrow)0.000
Bibliometrics0.000

Gemma

Not applicable0.948
Observational0.318
Simulation or modelling0.013
Research integrity0.003
Science and technology studies0.001
Non-randomized trial0.001
Metaresearch0.001
Bench or experimental0.001
Case report0.001
Theoretical or conceptual0.000
Randomized trial0.000
Open science0.000
Systematic review0.000
Scholarly communication0.000
Qualitative0.000
Meta-analysis0.000
Meta-epidemiology (narrow)0.000
Meta-epidemiology (broad)0.000
Bibliometrics0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.146
GPT teacher head0.479
Teacher spread
0.332 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

If you have ever doubted that pharmacologically potent compounds can be derived from plants, consider the history of warfarin. In the 1920s cattle in the Northern USA and Canada were afflicted by an outbreak of an unusual disease, characterised by fatal bleeding, either spontaneously or from minor injuries. Mouldy silage made from sweet clover (Melilotus alba and M. officinalis) was implicated, and L M Roderick in North Dakota showed that it contained a haemorrhagic factor that reduced the activ…

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.