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Record W2044394780 · doi:10.1159/000123453

In vitro Neurophysiology of Identified Rat Hypothalamic ‘Neuroendocrine’ Neurons

2008· article· en· W2044394780 on OpenAlexaff
Charles W. Bourque, Leo P. Renaud

Bibliographic record

VenueNeuroendocrinology · 2008
Typearticle
Languageen
FieldPsychology
TopicNeuroendocrine regulation and behavior
Canadian institutionsMcGill UniversityMontreal General Hospital
Fundersnot available
KeywordsEndocrinologyInternal medicineNeurophysiologyNeuroscienceHypothalamusIn vitroNeuroendocrinologyBiologyMedicineHormone

Abstract

fetched live from OpenAlex

Stable synaptic and antidromic electrophysiological recordings were obtained for 10-15 h from identified neurohypophyseal and tuberoinfundibular neurons using an acute explant of rat hypothalamus maintained in vitro through perfusion of the carotid artery with oxygenated artificial media. Synaptic potentials from preoptic and median eminence stimulation were blocked during perfusion with 12 m M Mg++-containing solutions. Antidromic and spontaneous action potentials recorded in neurohypophyseal neurons were followed by a transient after-hyperpolarization of 3-10 mV, due primarily to a brief increase in potassium conductance. Evidence favoring the existence of a synaptic recurrent inhibitory pathway was present in records obtained from tuberoinfundibular neurons, but not from neurohypophyseal cells.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.557
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.307
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2008
Admission routes1
Has abstractyes

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