OMS302 (phenylephrine and ketorolac injection) 1%/0.3% to maintain intraoperative pupil size and to prevent postoperative ocular pain in cataract surgery with intraocular lens replacement
Bibliographic record
Abstract
Cataract surgery with intraocular lens replacement is among the most commonly performed surgical procedures worldwide. Various pharmacologic agents are administered topically before and/or after, and a few are delivered intracamerally during, surgery to achieve mydriasis and to treat postoperative pain and inflammation. OMS302 (Omidria™ [phenylephrine and ketorolac injection] 1%/0.3%), a proprietary drug containing phenylephrine and ketorolac, was developed for use during cataract surgery to maintain intraoperative pupil size by preventing miosis and reduce early postoperative ocular pain. Containing no preservatives or bisulfites, OMS302 is formulated in a single-dose, single-patient use vial. Added to a standard 500 ml container of irrigation solution used during the procedure, OMS302 is infused into the anterior chamber with direct action on the iris and other ocular tissues. As the only US FDA-approved drug that is indicated both to prevent miosis and reduce postoperative pain associated with cataract surgery, OMS302 provides a new treatment option for ophthalmic surgeons.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".