Involvement of the Preoptic Region in Gonadotropin Release-Inhibition in Goldfish, Carassius auratus
Why this work is in the frame
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Bibliographic record
Abstract
Lesions were made in various hypothalamic and preoptic regions in sexually mature female and male goldfish. Destruction of the pituitary stalk, and lateral anterior hypothalamic tract areas caused ovulation and increased serum gonadotropin levels. Destruction of the entire preoptic region or a major part of the anterior nucleus preopticus periventricularis also caused ovulation and increased serum GtH levels. Lesions in other locations were ineffective. The results indicate that a gonadotropin release-inhibitory factor (GRIF) probably originates in the anterior preoptic region, and reaches the pituitary via pathways in the lateral preoptic and lateral anterior hypothalamic regions, and the pituitary stalk. The preovulatory surge of gonadotropin secretion may be regulated by release from inhibition exerted by GRIF in goldfish.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it