Feasibility of Transient Image-guided Blood-Spinal Cord Barrier Disruption
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
To evaluate the feasibility of disrupting the blood‐spinal cord barrier (BSCB), 31 rats were exposed to focused 1.08 MHz ultrasound at electrical powers of 0.5 W and 1.0 W after injection of the ultrasound contrast agent Definity. T1‐weighted images were acquired before and after ultrasound exposure using a 3 T MRI and the MR contrast agent Gadovist. At 0.5 and 1.0 W the average relative enhancements observed were 29.1±21% and 57.5±34% respectively. After recovery from ultrasound exposure, the rats did not show signs of motor impairment. The results demonstrate the feasibility of BSCB disruption using ultrasound together with ultrasound contrast agents. Further studies of this method are warranted.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it