A stochastic model for the self-similar heterogeneity of regional organ blood flow
Why this work is in the frame
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Bibliographic record
Abstract
The theory of exponential dispersion models was applied to construct a stochastic model for heterogeneities in regional organ blood flow as inferred from the deposition of labeled microspheres. The requirements that the dispersion model be additive (or reproductive), scale invariant, and represent a compound Poisson distribution, implied that the relative dispersion (RD = standard deviation/mean) of blood flow should exhibit self-similar scaling in macroscopic tissue samples of masses m and m(ref) such that RD(m) = RD(m(ref)). (m/m(ref))(1-D), where D was a constant. Under these circumstances this empirical relationship was a consequence of a compound Poisson-gamma distribution that represented macroscopic blood flow. The model also predicted that blood flow, at the microcirculatory level, should also be heterogeneous but obey a gamma distribution-a prediction supported by observation.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it