Termination Codons and Stop Codon Context in Bacteria and Mammalian Mitochondria
Why this work is in the frame
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Bibliographic record
Abstract
The aim of this study was to analyze the frequency of occurrence of individual stop codons and combinations of stop codons with adjacent upstream and downstream triplets in 264 bacterial and 1308 mammalian mitochondrial genomes. For the purpose of this analysis a novel program (Gene Triplet Analysis) was applied. The obtained results indicate that the standard stop codon UAA is the most frequently used one (48%) in both bacteria and mitochondria. In addition, our analysis revealed 30 nonstandard translation termination codons in mitochondria. The preferential nucleotides in all three positions adjacent to the stop codons in mammalian mitochondria are A and U.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it